An Edible Experience Without the Wait

At Satori, we’ve been making amazing, delicious cannabis-infused chocolates since 2015, focused on microdosed, chocolate-covered real fruits and nuts. Microdosing means that each piece contains a very small amount of THC, so that people can try edibles without worrying about becoming overwhelmingly high. 

Beyond proper dosing, another issue confronting new users of cannabis edibles is wait time. When ingested, cannabis is processed by the liver, and it can take up to two hours for effects to be fully felt. Sometimes, when people get impatient, they might eat more edibles because they don’t feel it kicking in yet, and this can cause issues when multiple doses begin to take effect. 

We don’t want people to have negative experiences with cannabis edibles, so we decided to look into ways to reduce the onset time. 

Currently, several companies are marketing “Fast-Acting” edibles made using a various types of nanotechnology, but we decided to use a nanoemulsifier called VESIsorb®, which is “ a naturally self-assembling colloidal droplet delivery system that has been clinically proven to increase absorption of nutritional supplements, food and beverage, and cosmetic ingredients.” It’s commonly used in the vitamin and supplement business to increase bioavailability of substances including omega-3 EFAs, coenzyme Q10, vitamin K2, curcumin, phytocannabinoids, vitamin D, krill oil, algal DHA, vitamin A and beta-caryophyllene.

Here at CannaCraft, we believe in being transparent about our ingredients while also remaining on the cutting edge of cannabinoid science. Matt Elmes is our Director of New Product Development, and he comes equipped with a Ph.D. in Molecular and Cellular Biology. In his opinion, VESIsorb® is the best option for increasing cannabinoid bioavailability because its efficacy is backed up with clinical research. VESIsorb® has previously been established as an effective way of increasing bioavailability of lipophilic vitamins such as CoQ10, and these exciting findings were recently extended to phytocannabinoids! Last year a randomized, double-blinded clinical trial was published comparing the relative uptake and bioavailability of CBD formulated with VESIsorb® compared to traditional oil-solubilized edibles.  These researchers found HUGE increases in how much CBD these patients were able to absorb into their bodies. They also found that the CBD was absorbed at a significantly faster rate compared to standard edible formulations. It really works! 

Starting in February of 2020, Satori Strawberries in Milk Chocolate are now made with VESIsorb®, greatly reducing onset time when compared to traditional edibles. 

Sourced from Italy, these delightfully chewy alpine strawberries are one of our best-selling products. Coated in chocolate and infused with pure cannabis oil, these award-winning confections now enable euphoric effects to be felt comparatively quickly versus the two-hour onset time for most other edibles.

How does VESIsorb® improve the absorption and bioavailability of phytocannabinoids?

Basically, VESIsorb® mimics the body’s natural methods of emulsification, which happen in our gastrointestinal tract, enabling humans to fully absorb nutrients and break down foodstuffs. Phytocannabinoids (like THC and CBD) found within the cannabis plant mix well with fats, but not water, so they require emulsification to be efficiently absorbed after ingestion. This process makes nutrients “bioavailable” to our bodies. Phytocannabinoids are not naturally water-soluble and exhibit poor bioavailability on their own, so much of their content is not absorbed at all during digestion, and the effects of THC and CBD aren’t utilized efficiently in our bodies. 

Once cannabinoids that are formulated with VESIsorb® hit your saliva and stomach juices, it spontaneously emulsifies into millions of microscopic ‘bubbles’ of emulsion droplets. The cannabinoids reside inside these tiny lipid droplets and they ‘trick’ your body into eagerly absorbing as much as possible, as quickly as possible.  

What is VESIsorb® made from?

The ingredients of the “VESIsorb® Colloidal Droplet Delivery System” include medium chain triglycerides, non-ionic surfactant, polyglycerol esters of fatty acids, and natural flavors. While some of these ingredients might sound unfamiliar and therefore frightening, there’s really nothing to be worried about. 

Medium chain triglycerides (MCT) are a natural product that makes up part of coconut oil. "Surfactant" stands for "surface active agent,” a compound that lowers surface tension, and stabilizes the mixture. Nonionic surfactants are molecules with no electrical charge. An emulsifier, polyglycerol esters of fatty acids (PGEs) are frequently used in food, pharmaceutical, and cosmetic industries on account of their amphiphilic properties.

For more information, check out this video about VESIsorb®.

Want to try our new fast-acting Strawberries in Milk Chocolate? Order online and pick them up at a local dispensary.